{
  "updates": [
    {
      "sku": "E42",
      "name": "Neoscript RTase Ⅱ",
      "generation": "3代",
      "scenes": [
        "LAMP-探针法 · — · RNA"
      ],
      "prios": [
        "液体①"
      ],
      "evidence": "①可用于肠道项目/性病项目，探针法\n②需要拟单变成含甘油版本，Bst3.0 HS\n①可用于肠道项目/性病项目，探针法",
      "suggest": [],
      "pending": [],
      "old_targets": "LAMP探针法",
      "old_fast": "—",
      "old_premix": "—",
      "old_lyo": "【待补】",
      "old_protectant": "—"
    },
    {
      "sku": "M216",
      "name": "2×Robustart Premix (Probe qPCR)",
      "generation": "1代",
      "scenes": [
        "SNP · taqman/MGB · DNA/RNA",
        "甲基化 · — · DNA"
      ],
      "prios": [
        "液体①",
        "液体③",
        "液体②"
      ],
      "evidence": "①③适合高GC\n②适配多个SNP体系，但是不适合高GC（60%）\n①特异性好\n②冻干球 55℃加速 45d扩增性能基本稳定\n有客户采购，效果还行\n---\n①比②的耐抑制性更佳，与②主酶不同",
      "suggest": [
        "快速",
        "全预混",
        "验证数据"
      ],
      "pending": [],
      "old_targets": "SNP；micro RNA；甲基化；肿瘤",
      "old_fast": "—",
      "old_premix": "—",
      "old_lyo": "是",
      "old_protectant": "AS412-9、AS412-9冻干保护剂"
    },
    {
      "sku": "M2161",
      "name": "2×Robustart Premix-UNG (Probe qPCR)",
      "generation": "1代",
      "scenes": [
        "SNP · ARMS · DNA/RNA"
      ],
      "prios": [
        "液体④"
      ],
      "evidence": "①灵敏度、特异性比较好",
      "suggest": [
        "全预混"
      ],
      "pending": [],
      "old_targets": "SNP；ARMS；mRNA",
      "old_fast": "—",
      "old_premix": "—",
      "old_lyo": "是",
      "old_protectant": "AS212-9-T1"
    },
    {
      "sku": "M5244",
      "name": "5×Neoscript Fast RT Premix-UNG (Probe qRT-PCR)",
      "generation": "1代（同系列）",
      "scenes": [
        "动物疫病 / 蓝耳 · taqman · RNA"
      ],
      "prios": [
        "液体②",
        "液体③"
      ],
      "evidence": "①MD2104-003001单管稳定性效果比MD2104-000814好\n②M5244-073701检测下限附近，灵敏度好，全预混稳定性不行\n③有较多客户用在蓝耳上面\n①冻干球55℃加速15d扩增性能基本稳定",
      "suggest": [
        "全预混",
        "验证数据"
      ],
      "pending": [],
      "old_targets": "动物疫病",
      "old_fast": "中（普通快速）",
      "old_premix": "—",
      "old_lyo": "是",
      "old_protectant": "AS212-000901-T2"
    },
    {
      "sku": "M2181-4",
      "name": "2×FastAmpli Premix-UNG Ⅳ (Probe qPCR)",
      "generation": "2代",
      "scenes": [
        "结核 · taqman · —",
        "公卫/呼吸道/肠道病原体 · MeltArray熔曲 · —",
        "HPV · MMCA · DNA",
        "HPV · taqman · —"
      ],
      "prios": [
        "液体③",
        "液体②"
      ],
      "evidence": "有客户使用效果还行\n有客户采购，效果还行\n---\n①06相对05做了Tm值的提升\n---\n①可用于MTB项目。M3291-2 单管2-8℃ 1M基本稳定，但有个别靶标峰高下降50%。最快可做1h27min。\n①冻干粉37℃ 2M基本稳定；冻干球37℃ 14d扩增性能基本稳定\n②冻干粉55℃加速 30d扩增性能基本稳定，冻干球常温18个月扩增性能基本稳定\n---\n①抗抑制性好\n②③有客户采购，③主要基于②在个别客户引探下对16、18型的扩增线型有改善\n有客户采购，效果还行\n①冻干粉55℃加速 30d扩增性能基本稳定，冻干球常温18个月扩增性能基本稳定",
      "suggest": [
        "全预混",
        "验证数据"
      ],
      "pending": [
        "源表HPV/MMCA特征疑似串行，未作为已验证结论"
      ],
      "old_targets": "结核；呼吸道/肠道；HPV；动物疫病；SNP",
      "old_fast": "中（普通快速）",
      "old_premix": "—",
      "old_lyo": "是",
      "old_protectant": "AS412-9、AS212-000901-T2、AS212-000901、AS212-9-T1"
    },
    {
      "sku": "MD2091",
      "name": "2×SensiDirect Premix-UNG (Probe qPCR)",
      "generation": "2代",
      "scenes": [
        "HPV · taqman · —",
        "单管全预混 · taqman · DNA"
      ],
      "prios": [
        "液体①"
      ],
      "evidence": "①抗抑制性好\n②③有客户采购，③主要基于②在个别客户引探下对16、18型的扩增线型有改善\n有客户采购，效果还行\n①冻干粉55℃加速 30d扩增性能基本稳定，冻干球常温18个月扩增性能基本稳定\n---\n①MD2091单管2-8℃保存1年基本保持稳定，且比MD2071抗干扰效果更好\n②M2181-4-095203单管37℃加速7天基本保持稳定\n③M2331单管37度1个月、2-8℃或室温保存6个月基本保持稳定",
      "suggest": [
        "验证数据"
      ],
      "pending": [],
      "old_targets": "HPV；单管全预混；结核；动物疫病",
      "old_fast": "中（普通快速）",
      "old_premix": "是",
      "old_lyo": "是",
      "old_protectant": "AS212-9-T1"
    },
    {
      "sku": "MD2111",
      "name": "2×Stool Direct Premix-UNG (Probe qPCR)",
      "generation": "2代",
      "scenes": [
        "肠道-粪便直扩 · taqman · DNA"
      ],
      "prios": [
        "液体①"
      ],
      "evidence": "冻干粉55℃加速 30d扩增性能基本稳定",
      "suggest": [
        "快速",
        "全预混",
        "验证数据"
      ],
      "pending": [],
      "old_targets": "肠道/粪便直扩",
      "old_fast": "—",
      "old_premix": "—",
      "old_lyo": "是",
      "old_protectant": "AS412-9"
    },
    {
      "sku": "MD2084",
      "name": "2×Fast Direct RT Premix-UNG (Probe qRT-PCR)",
      "generation": "2代",
      "scenes": [
        "动物疫病 / 水产 · — · RNA"
      ],
      "prios": [
        "液体②"
      ],
      "evidence": "①可裂解液直扩\n②适配性好\n①和②用于水产项目，单靶标/多靶标，效果相当，部分靶标814-Rn值略低\n③用于动物疫病，多靶标\n④用于水产项目、动物疫病，单靶标，冻干球55℃加速 30d扩增性能基本稳定",
      "suggest": [
        "快速",
        "全预混",
        "验证数据"
      ],
      "pending": [],
      "old_targets": "动物疫病",
      "old_fast": "—",
      "old_premix": "—",
      "old_lyo": "【待补】",
      "old_protectant": "—"
    },
    {
      "sku": "MD2124",
      "name": "2×Stool Direct RT Premix-UNG (Probe qRT-PCR) (T1)",
      "generation": "2代",
      "scenes": [
        "肠道-粪便直扩 · — · RNA"
      ],
      "prios": [
        "液体②"
      ],
      "evidence": "",
      "suggest": [
        "快速",
        "全预混"
      ],
      "pending": [],
      "old_targets": "肠道/粪便直扩",
      "old_fast": "—",
      "old_premix": "—",
      "old_lyo": "【待补】",
      "old_protectant": "—"
    },
    {
      "sku": "M2281",
      "name": "2×Robustart ARMS Gene-typing Premix-UNG (Probe qPCR)",
      "generation": "3代",
      "scenes": [
        "SNP · ARMS · DNA/RNA"
      ],
      "prios": [
        "液体③"
      ],
      "evidence": "①灵敏度、特异性比较好",
      "suggest": [
        "全预混"
      ],
      "pending": [],
      "old_targets": "SNP；ARMS",
      "old_fast": "—",
      "old_premix": "—",
      "old_lyo": "是",
      "old_protectant": "AS212-9-T1"
    },
    {
      "sku": "MD2104-003006",
      "name": "2×SensiDirect RT Premix-UNG (Probe qRT-PCR)",
      "generation": "3代（同系列）",
      "scenes": [
        "公卫/呼吸道/肠道病原体 · taqman · DNA/RNA",
        "单管全预混 · — · RNA"
      ],
      "prios": [
        "液体②",
        "液体①"
      ],
      "evidence": "①呼吸道优化体系，多靶标，特异性还行，适合酸性释放剂\n②病原体检测，公卫项目，单管全预混，稳定性还不错，37度加速3d，稳定性可以，扩增性能稳定\n③适配性好，灵敏度和稳定性好\n④是新体系，超快速，用宏石48SC，时间为15min16s\n⑤RT单管，适配性好，公卫项目\n①为FMD6104-020322的冻干体系，呼吸道项目，冻干球50℃加速20d扩增性能基本稳定\n②只做超快速，特异性好，公卫、肠道、呼吸道项目均可，冻干球55℃加速7d、常温8个月扩增性能基本稳定\n④体系灵敏度最高，冻干球55℃加速15d扩增性能基本稳定（搭配AS212-000901-T2）\n⑤超快速体系，冻干球55℃加速14d扩增性能基本稳定，部分靶标低浓度Rn下降20%以内。\n---\n①MD2104-003006体系37℃全预混加速6d基本保持稳定\n②MD2104-092401体系可耐受10mM异硫氰酸胍和5%无水乙醇，37℃全预混加速4d基本稳定。\n③M2274-088901单管37℃加速7d多数靶标基本保持稳定，不可做快速程序",
      "suggest": [
        "快速",
        "验证数据"
      ],
      "pending": [],
      "old_targets": "呼吸道/肠道；单管全预混",
      "old_fast": "—",
      "old_premix": "是",
      "old_lyo": "是",
      "old_protectant": "AS212-000901-T2、AS212-9-T1、AS212-000901、AS412-9"
    },
    {
      "sku": "MD2104-014429",
      "name": "2×SensiDirect RT Premix-UNG (Probe qRT-PCR)",
      "generation": "3代（极速/场景补充）",
      "scenes": [
        "公卫/呼吸道/肠道病原体 · taqman · DNA/RNA"
      ],
      "prios": [
        "液体④"
      ],
      "evidence": "①呼吸道优化体系，多靶标，特异性还行，适合酸性释放剂\n②病原体检测，公卫项目，单管全预混，稳定性还不错，37度加速3d，稳定性可以，扩增性能稳定\n③适配性好，灵敏度和稳定性好\n④是新体系，超快速，用宏石48SC，时间为15min16s\n⑤RT单管，适配性好，公卫项目\n①为FMD6104-020322的冻干体系，呼吸道项目，冻干球50℃加速20d扩增性能基本稳定\n②只做超快速，特异性好，公卫、肠道、呼吸道项目均可，冻干球55℃加速7d、常温8个月扩增性能基本稳定\n④体系灵敏度最高，冻干球55℃加速15d扩增性能基本稳定（搭配AS212-000901-T2）\n⑤超快速体系，冻干球55℃加速14d扩增性能基本稳定，部分靶标低浓度Rn下降20%以内。",
      "suggest": [
        "全预混",
        "验证数据"
      ],
      "pending": [],
      "old_targets": "呼吸道/肠道",
      "old_fast": "强（极速）",
      "old_premix": "—",
      "old_lyo": "是",
      "old_protectant": "AS212-000901-T2、AS212-9-T1、AS212-000901、AS412-9"
    },
    {
      "sku": "E105",
      "name": "Bst 3.0 HS",
      "generation": "2代",
      "scenes": [
        "LAMP-探针法 · — · RNA"
      ],
      "prios": [
        "液体①"
      ],
      "evidence": "①可用于肠道项目/性病项目，探针法\n②需要拟单变成含甘油版本，Bst3.0 HS\n①可用于肠道项目/性病项目，探针法",
      "suggest": [],
      "pending": [],
      "old_targets": "LAMP探针法",
      "old_fast": "—",
      "old_premix": "—",
      "old_lyo": "【待补】",
      "old_protectant": "—"
    },
    {
      "sku": "HW205",
      "name": "Colorimetric Lamp Kit (RY) (Bst2.0 HS)",
      "generation": "2代",
      "scenes": [
        "LAMP-染料法 · — · DNA",
        "LAMP-探针法 · — · DNA"
      ],
      "prios": [
        "液体①"
      ],
      "evidence": "Bst3.0 HS",
      "suggest": [],
      "pending": [],
      "old_targets": "LAMP染料法；LAMP探针法",
      "old_fast": "—",
      "old_premix": "—",
      "old_lyo": "【待补】",
      "old_protectant": "—"
    },
    {
      "sku": "HW206",
      "name": "Colorimetric RT Lamp Kit (RY) (Bst2.0 HS)",
      "generation": "2代",
      "scenes": [
        "LAMP-染料法 · — · RNA"
      ],
      "prios": [
        "液体①"
      ],
      "evidence": "Bst3.0 HS",
      "suggest": [],
      "pending": [],
      "old_targets": "LAMP染料法",
      "old_fast": "—",
      "old_premix": "—",
      "old_lyo": "【待补】",
      "old_protectant": "—"
    }
  ],
  "main_changes": [
    [
      49,
      "适用靶标/客户项目",
      "【待补】",
      "熔曲",
      "XMind 迭代关系图"
    ]
  ],
  "chain": [],
  "new_skus": [
    [
      "M5274-073703",
      "202611 单管全预混 RNA 第④推荐；V01 无此货号",
      "待产品主数据确认",
      "202611-产品推荐清单"
    ],
    [
      "MD2104-092401",
      "202611 单管全预混 RNA 第②推荐；V01 有 M2104-092401（少 D），需确认是否同一产品",
      "疑似货号/书写差异",
      "202611-产品推荐清单"
    ],
    [
      "M216-085201",
      "202611 甲基化 第①推荐；V01 只有 M216",
      "待产品主数据确认",
      "202611-产品推荐清单"
    ],
    [
      "M216-SM1",
      "202611 甲基化 第③推荐；V01 只有 M216",
      "待产品主数据确认",
      "202611-产品推荐清单"
    ],
    [
      "M2181-4-NA",
      "202611 公卫 taqman DNA 第④推荐；V01 只有 M2181-4",
      "变体/待产品主数据确认",
      "202611-产品推荐清单"
    ],
    [
      "M2221-001110",
      "202611 非瘟 第③推荐；V01 无此货号；202608 为 M2221-001112",
      "货号变更待确认",
      "202611-产品推荐清单"
    ]
  ]
}